ABSTRACT

Hypertensive disorders in pregnancy, particularly preeclampsia, represent a global public health issue and are the leading cause of maternal mortality in Brazil, accounting for 20% of maternal deaths. Despite advancements in prevention, disparities persist, especially in low- and middle-income countries, where calcium intake is often below recommended levels. This article reviews the evidence supporting calcium supplementation as an effective strategy for preventing preeclampsia, with benefits extending beyond blood pressure control. Systematic review data from the Cochrane Library highlight a reduction in preeclampsia, maternal morbidity, and preterm birth among women who supplement and have low calcium intake. However, recent debates have questioned the universality of this recommendation, suggesting supplementation only for high-risk pregnancies. These controversies arise from methodological limitations in sensitivity analyses and misinterpretations. Nevertheless, the World Health Organization guidelines advocate calcium supplementation of 1.5-2 g/day for pregnant women in regions with low calcium intake. This recommendation aligns with findings demonstrating improved maternal and neonatal outcomes, emphasizing the need for widespread implementation. Urgent national policies in Brazil are required to ensure equitable access to calcium, particularly given the high prevalence of preeclampsia and maternal mortality.

Keywords: High-risk pregnancy, Calcium, Preeclampsia, Maternal mortality, Public health

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